Multifactor Dimensionality Reduction (
MDR) was originally developed to detect gene-gene interactions in the domain of human genetics.
MDR uses constructive induction to capture interaction information. The open-source
MDR software package is available in Java and comes with an easy to use GUI with many interactive features including graphical output. For more information see:
References
Moore JH. Computational analysis of gene-gene interactions using multifactor dimensionality reduction. Expert Rev Mol Diagn. 2004 Nov;4(6):795-803.